Cholera
Cholera is endemic in the Philippines. Through a grant from UPM-NIH, investigators from ICHHD, together with the Philippines’ Department of Health and Johns Hopkins University, collated and analyzed available surveillance data from the country from 2008-2013. The findings in this study as well as heat maps showing areas where suspected and confirmed cholera cases were published in 2015. The maps are useful in identifying areas that may be targeted for future control efforts.
Although clean water and sanitation are the mainstays for cholera control, the World Health Organization has recommended the use of oral cholera vaccines (OCVs) as an additional measure against cholera. Since 2001, OCVs have been available internationally; however, the cost of the vaccine made it only available for travelers from developed countries going to cholera-endemic countries. With the availability of newer, lower-cost OCVs, the vaccines became more widely available even to lower- and middle-income countries where cholera remains a problem. In 2014, in collaboration with the Johns Hopkins Bloomberg School of Public Health, the ICHHD organized a workshop aimed at providing information on how OCV can become a part of an integrated response for cholera control.
-
Cholera in selected countries in Asia. https://doi.org/10.1016/j.vaccine.2019.07.035
Cholera prevention and control in Asian countries. https://doi.org/10.1186/s12919-018-0158-1
Immunogenicity of protection from a single dose of internationally available killed oral cholera vaccine: a systematic review and meta-analysis. https://doi.org/10.1093/cid/cix1039
Cholera outbreak in Yemen. https://doi.org/10.1016/S2468-1253(17)30287-X
Evaluation in Cameroon of a novel, simplified methodology to assist molecular microbiological analysis of V. cholerae in resource-limited settings. https://doi.org/10.1371/journal.pntd.0004307
Validity of the estimates of oral cholera vaccine effectiveness derived from the test-negative design. https://doi.org/10.1016/j.vaccine.2015.12.004
The scenario approach for countries considering the addition of oral cholera vaccination in cholera preparedness and control plans. https://doi.org/10.1016/S1473-3099(15)00298-4
Trials and tribulations of conducting interventional studies in urban slums of a developing country: Experiences from Kolkata, India. https://doi.org/10.1080/21645515.2015.1066052
Assessing different measures of population-level vaccine protection using a case-control study. https://doi.org/10.1016/j.vaccine.2015.07.045
Peru-15 (Choleragarde(®)), a live attenuated oral cholera vaccine, is safe and immunogenic in human immunodeficiency virus (HIV)-seropositive adults in Thailand. https://doi.org/10.1016/j.vaccine.2015.07.073
Updated global burden of cholera in endemic countries. https://doi.org/10.1371/journal.pntd.0003832
Flexibility of oral cholera vaccine dosing––a randomised controlled trial measuring immune responses following alternative vaccination schedules in a cholera hyper-endemic zone. https://doi.org/10.1371/journal.pntd.0003574
Epidemiology of cholera in the Philippines. https://doi.org/10.1371/journal.pntd.0003440
Post-licensure deployment of oral cholera vaccine: a systematic review. https://doi.org/10.2471/BLT.14.139949
Killed oral cholera vaccines: history development and implementation challenges. https://doi.org/10.1177/2051013614537819
Vibrocidal antibody responses to a bivalent killed whole-cell oral cholera vaccine in a Phase III trial in Kolkata, India. https://doi.org/10.1371/journal.pone.0096499
Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the Odisha Model. https://doi.org/10.1371/journal.pntd.0002629
Risk map of cholera infection for vaccine deployment: the Eastern Kolkata, India. https://doi.org/10.1371/journal.pone.0071173
