Environmental Toxicants
Through a grant from the Eunice Kennedy Shriver National Institute of Health and Human Development (NICHD) of the US-NIH and the US Environmental Protection Agency, Dr. Enrique M. Ostrea Jr., a full-time tenured Professor of Pediatrics at Wayne State University and an Adjunct Research Professor at ICHHD, collaborated on the study Fetal Exposure to Environmental Toxicants and Infant/Child Outcomes. He received simultaneous research grants to identify environmental toxicants in newborn infants through meconium testing and determined pertinent infant outcomes. Ostrea received a continuing grant from the US-NICHD to follow-up mother-infant dyads up to 6 years of age.
Conducting the Wechsler Adult Intelligence Scale (WAIS) test to determine maternal IQ.
A total of 716 mother-infant dyads were followed up until the children reached 6 years of age (99% follow-up rate). The mean full IQ score was 83.6 (±8.6) at 6 years old. Prenatal but not post-natal exposure to household pesticides, such as propoxur and pyrethroids, was found to negatively affect the child’s IQ at 4 years old significantly. Confounders affecting the child’s IQ like maternal IQ; child’s weight, height, and head circumferences; socio-economic status; and home stimulation scores should be considered aside from prenatal exposures.
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Trends in long-term exposure to propoxur and pyrethroids in young children in the Philippines. https://doi.org/10.1016/j.envres.2014.01.003
Fetal exposure to propoxur and abnormal child neurodevelopment at 2 years of age. https://doi.org/10.1016/j.neuro.2011.11.006
Analysis of house dust and children’s hair for pesticides: A comparison of markers on ongoing pesticide exposure in children. https://doi.org/10.4172/1948-593X.1000057
Use of the Griffiths Mental Development Scales in an argo-industrial province in the Philippines. https://doi.org/10.1111/j.1365-2214.2010.01080.x
An epidemiologic study comparing fetal exposure to tobacco smoke in three Southeast Asian countries. https://doi.org/10.1179/oeh.2008.14.4.257
Combined analysis of prenatal (maternal hair and blood) and neonatal (infant hair, cord blood and meconium) matrices to detect fetal exposure to environmental pesticides. https://doi.org/10.1016/j.envres.2008.09.004
Persistent pulmonary hypertension of the newborn. https://doi.org/10.2165/00148581-200608030-00004
